Highest OS for Pan6?

May I ask a very basic question?

What is the highest OS that allows Pan6 to be run directly, that is, without relying on Parallels or other “virtual” environments? I use El Capitain (OS 10.11.6) now. What is the highest upgraded OS that will keep my system intact without also upgrading to PanX (for now).

Vic

I believe that would be Mojave, 10.14.

I use Mojave and it works great with Panorama 6