Apple has just released OS 10.12.2. Some recommendations in a newsletter I received from Cocktail may be relevant to people who've had problems with Pan X on 10.12.1:
"Please note that it is always recommended to use a combo update to update macOS.
Many of the problems we are asked to solve can be traced back to a faulty system update or corrupt system files. While it may sound pretty serious there is usually a very simple way to fix it, reinstall the latest Combo update from Apple.
When Apple is testing macOS updates with its developers they are using the Combo update, which is a package that contains every single update from the day your macOS version was released. However, what they deliver to the end users is normally an incremental update which only contains the changes from say 10.12.1 to 10.12.2. Unless you have a clean install there is a chance that it will replace files it shouldn’t or, on the contrary, that it won’t replace files that have become corrupted and are now causing problems.
The best thing to do if you happen to experience these problems is to reinstall the update, but instead of using the Mac App Store which will only give you the incremental update you use the Combo update. The Combo update will replace all the core system files and give you a completely fresh and up to date macOS install that will hopefully make your problems history.
This is also how you fix your computer if an update was interrupted as the Combo update will restore all missing files and make sure they are up to date.
You can download the macOS Sierra 10.12.2 Combo Update from https://support.apple.com/kb/DL1900.